What is a contraindication for using NSAIDs like Toradol in a patient suspected of having kidney stones?

In the context of kidney stones, severe dehydration is a significant concern because it compromises renal function and can exacerbate existing kidney issues. NSAIDs, such as Toradol, can lead to further renal impairment, especially in a dehydrated state. They have the potential to reduce renal blood flow by inhibiting prostaglandin synthesis, which can result in acute kidney injury, particularly in patients who are already at risk due to dehydration. Therefore, using NSAIDs in a patient with suspected kidney stones and severe dehydration may worsen their renal condition.

While gastrointestinal bleeds, recent surgery, and known allergies to NSAIDs are important factors to consider, they do not specifically underline the renal risks associated with NSAID use in a patient already facing potential kidney complications from kidney stones. Thus, severe dehydration stands out as a direct contraindication in this scenario.