What is the recommended post-exposure prophylaxis for HIV?

The recommended post-exposure prophylaxis for HIV is antiretroviral therapy administered within 72 hours after potential exposure to the virus. This intervention is crucial because it significantly reduces the risk of HIV infection if started promptly. The guidelines emphasize the importance of initiating this therapy as soon as possible, ideally within hours of the exposure, but definitely within the 72-hour window to maximize its effectiveness.

By using a combination of antiretroviral medications, this therapy works to suppress the replication of the virus in case any particles have entered the bloodstream. The aim is to prevent the establishment of a permanent infection and is particularly vital for anyone potentially exposed through high-risk activities such as needle sharing or unprotected sexual encounters.

Options that involve other methods, such as intravenous immunoglobulin therapy, regular blood donations, or simply monitoring for symptoms, do not provide an effective means of preventing HIV infection post-exposure and are not recommended by health authorities. These alternatives either lack evidence supporting their efficacy in preventing HIV or would not provide timely intervention necessary to combat the virus before it takes hold in the body.